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Vital Signs

Perspectives on Healthcare IT, clinical informatics, emerging technology, and life at the intersection of nursing and enterprise systems.

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October 28, 2026 · Certification Prep, Healthcare IT, HIMSS Word of The Day, Interoperability and Standards

HIMSS Word of the Day #216: XDS (Cross-Enterprise Document Sharing)

Cross-Enterprise Document Sharing, or XDS, is an Integrating the Healthcare Enterprise profile for registering, locating, and retrieving clinical documents across organizations. This post explains the registry and repository model, what an affinity domain is, what XDS does not do, and what recent studies say about technical implementation and governance.

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